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Bhupal Govinda Shrestha

KU-staff
Associate Professor,
Department of Biotechnology, School of Science
Dirghayu Tole, Shantinagar, Baneshwor, Kathmandu
9851163725
bgs@ku.edu.np
Bio
Honors and Awards
Research
Publication
Biography

Bhupal Govinda Shrestha, PhD, has almost 20 years of experience in the field of Biotechnology. He did his Masters in Nutritional Biochemistry and PhD in Molecular/Cancer Biology from Tokyo University of Agriculture, Japan. He has also done post doc from University of British Colombia, Vancouver, Canada and German Cancer Research Center, University of Heidelberg, Germany. He has also received trainings in ICGEB, New Delhi, Mahidol University, Thailand and Intellectual Property Rights. His Research interest is in medicinal plants and its anti-cancer activity and Bioenergy. His main area of Specialization is in Cancer Biology, Animal cell culture, mouse and drosophila models of cancer and Bioethanol.

Honors and Awards

Rotary Scholarship during Masters Degree

Japanese Govt. (Monbukagakusho) Scholarship during PhD 

Mahendra Bidhya Bhusan 'KA'

Editorial Board Member of National and International Journals

Many National and International Research Grants

Member of many Professional Organizations

Research

1) To study the anti cancer activity of Medicinal Plants of Nepal and elucidate their mechanism of action.

2) To isolate pure compounds from Natural Products

3) Bioenergy from agricultural wastes

Publication
  • Sudarshan Lamichhane, Raj Prateek Rai, Amar Khatri, Rajendra Adhikari, Bhupal Govinda Shrestha & Simon Kumar Shrestha (2021). Screening of phytochemicals as potential anti-breast cancer agents targeting HER2: an in-silico approach.. Journal of Biomolecular Structure and Dynamics,
  • Hom Bahadur Baniya, Pabitra Khadka, Sudip Pandey, Anusuya Nepal, Rajesh Prakash Guragain, Tika Ram Lamichhane, Santosh Dhungana, Bhupal Govinda Shrestha, Deepak Prasad Subedi (2021). Characterization of Cold Atmospheric Pressure Plasma Technology and Its Application in Biomedicine. Plasma Medicine
  • R Joshi, B Acharya, K Bhandari, S Bhandari, R Duwal, R Ghimire, Rajani Shakya, Kamal A Sweidan, Bhupal G Shrestha (2020). Dichloroacetyl chloride conjugated peptide-based probes: design, synthesis, and in vitro evaluation in breast cancer cells. International Journal of Polymeric Materials and Polymeric Biomaterials
  • JP Gurung, DP Subedi, R Shrestha, BG Shrestha (2020). Application of Atmospheric Pressure Argon Plasma Jet (APAPJ) in Biomedical Science and Engineering. Journal of Tropical Life Science
  • Binayak Raj Pandey, Sanjaya Ghimire, Shakep Bhattarai, Eileen Shrestha, Pratiksha Thapa, Bhupal Govinda Shrestha (2019). Isolation, growth, enzyme assay and identification via 16S rRNA full sequencing of cellulolytic microbes from Nepal for biofuel production. Renewable Energy
  • Binayak Raj Pandey, Angela Shrestha, Nisha Sharma, Bhupal Govinda Shrestha (2019). Evaluation of Phytochemical, Antimicrobial, Antioxidant Activity and Cytotoxic Potentials of Agave americana. Nepal journal of Biotechnology
  • Jaya Bhandari, BushraTaj Muhammad, Pratiksha Thapa and Bhupal Govinda Shrestha (2017). Study of phytochemical, anti-microbial, anti-oxidant, and anti-cancer properties of Allium wallichii.. BMC Complementary and Alternative Medicine
  • Jaya Bhandari, Pratiksha Thapa, Prasodhan Niraula,Nita Thapa, Nikita Shrestha, Bhupal Govinda Shrestha (2017). Study of Phytochemical, Anti-Microbial, Anti-Oxidant, Phytotoxic, and Immunomodulatory Activity Properties of Bauhinia variegata . Journal of Tropical Life Science
  • Anil Singh Basnyat , Abhimanyu Jha , R Pathak , Bhupal Govinda Shrestha (2017). Study of Serum Lactate Dehydrogenase and Gamma-Glutamyl Transpeptidase in Breast Cancer Patients Receiving Chemotherapy. The journal of tropical life science
  • Biplab KC, Siddhi Nath Paudel, Sagar Rayamajhi, Deepak Karna, Sandeep Adhikari, Bhupal G. Shrestha and Gunjan Bisht (2016). Enhanced preferential cytotoxicity through surface modification: synthesis, characterization and comparative in vitro evaluation of TritonX 100 modified and unmodified zinc oxide nanoparticles in human breast cancer cell line (MDA MB 231). Chemistry Central Journal
  • Sanjaya Ghimire, Shakep Bhattarai, Sailesh Phuyal, Bimal Thapa and Bhupal Govinda Shrestha (2016). Isolation and Screening of Potential Cellulolytic and Xylanolytic Bacteria from Soil Sample for Degradation of Lignocellulosic Biomass.. Journal of Tropical Life Science
  • Gunjan Bisht, Sagar Rayamajhi, Biplab KC, Siddhi Nath Paudel, Deepak Karna and Bhupal G. Shrestha (2016). Synthesis, Characterization, and Study of In Vitro Cytotoxicity of ZnO-Fe3O4 Magnetic Composite Nanoparticles in Human Breast Cancer Cell Line (MDA-MB-231) and Mouse Fibroblast (NIH 3T3). Nanoscale Research Letters
  • Nita Thapa, Pratiksha Thapa, Jay Bhandari, Prasodhan Niraula, Nikita Shrestha, Bhupal G. Shrestha (2016). Study of Phytochemical, Antioxidant and Antimicrobial Activity of Artocarpus heterophyllus. Nepal journal of Biotechnology
  • Anil Singh Basnyat, Prabin Gyawali, Abimanyu Jha, Prabodh Risal, Bhupal Govinda Shrestha (2016). Evaluation of Serum Lipids and C-peptide among Breast Cancer Patients with Chemotherapy. ACCLM
  • S Adhikari, B Lamichhane, P Shrestha, BG Shrestha (2015). Effect of Invitro Zinc (II) supplementation on Normal and Cancer Cell lines. International Journal for Research in Applied Science & Engineering Technology
  • Pritish Shrestha, Sandeep Adhikari, Basanta Lamichhane, Bhupal Govinda Shrestha (2015). Phytochemical Screening of the Medicinal Plants of Nepal. Journal of Environmental Science, Toxicology and Food Technology
  • Pritish Shrestha, Manisha Bista, Prativa Sharma, Shristi Shrestha, Basanta Lamichhane, Sandeep Adhikari, Binayak Raj Pandey, Bhupal Govinda Shrestha (2015). Phytochemical Screening, Antimicrobial Activity and Cytotoxicity of Nepalese Medicinal Plants,Swertia chirayita and Dendrobium amoenum . Nepal journal of Biotechnology
  • Jaya Bhandari, Asma Naqvi, Prasodhan Niraula, Pratikshya Thapa, Nita Thapa, Nikita Shrestha and Bhupal Govinda Shrestha (2015). Phytochemical screening, antioxidant assay of juniperus recurva and study of it’s in vitro cytotoxicity against breast cancer cell lines’. International Journal of Pharma and Bio Sciences, 6(3): 1134 – 1145
  • Basanta Lamichhane, Sandeep Adhikari, Pritish Shrestha, Bhupal Govinda Shrestha (2014). Study of phytochemical, antioxidant, antimicrobial and anticancer activity of Berberis Aristata. Journal of tropical Life Science, Vol 4, No 1
  • Pranita Kaphle, Srishti Rana, Jay Bhandari, Asha Bhandari, Richa Aishwarya, Tika Bahadur Karki, Bhupal Govinda Shrestha (2014). Isolation and Optimization of Cellulolytic and Xylanolytic Microbes from Nepal and their Utilization for Lignocellulosic Biomass Degradation. International Journal of Interdisciplinary and Multidisciplinary Studies (IJIMS), Vol 1, No.4, 1-10
  • Pranita Kaphle, Asha Bhandari, Srishti Rana, Sandeep Adhikari, Tika Bahadur Karki, Bhupal Govinda Shrestha (2013). Characterization and functional significance of cellulolytic and xylanolytic microbes isolated from Nepal and their utilization for lignocellulosic biomass degradation’. Rentech Symposium, Compendium, Vol 3
  • Pranita Kaphle, Asha Bhandari, Srishti Rana, Sandeep Adhikari, Tika Bahadur Karki, Bhupal Govinda Shrestha (2012). To study the potentiality of agriculture wastes as a source of xylose/glucose for production of ethanol and using it as biofuel’. Rentech Symposium, Compendium, Vol 2
  • Srishti Rana, Sandeep Adhikari, Tika Bahadur Karki, Bhupal Govinda Shrestha (2012). To study the potentiality of agriculture wastes as a source of xylose/glucose for production of ethanol and using it as biofuel. Rentech Symposium, Compendium, Vol 1
  • Raunak Shrestha, Rubin Narayan Joshi, Kriti Joshi, Bal Hari Poudel and Bhupal Govinda Shrestha (2011). Analysis of KatG Ser315Thr Mutation in Multidrug Resistant Mycobacterium tuberculosis and SLC11A1 Polymorphism in Multidrug Resistance Tuberculosis in Central Development Region of Nepal Using PCR‐RFLP Technique: A Pilot Study’. Nepal journal of Biotechnology. Vol. 1, No 1:14-21
  • BG Shrestha, A Teramoto, Ken-Ichi Kobayashi, Y Yamamoto, and T Tadokoro (2009). Physiological Study of Mustard Oil feeding of rats. J for the Integrated Study of Dietary Habits, Vol. 19, No. 4,:334-340.
  • Nishanta Saxena, Bhupal Govinda Shrestha, Tetsuro Ishii, Sunil Kaul and Renu Wadhwa (2009). Mortalin-Bcl-2 Interaction Act as a Tumor Suppressor Mechanism in Cancer Cells. Proceedings of the 2nd China Japan graduate Students Forum
  • N Widodo, Y Takagi, BG Shrestha, Tetsuro Ishii, SC Kaul and R Wadhwa (2008). Selective killing of cancer cells by leaf extract of Ashwagandha: Components, activity and pathway analyses. Cancer Letters
  • N Widodo,K Kaur, BG Shrestha,A Nagpal, Y Takagi, SC Kaul and R Wadhwa (2007 ). Selective Killing of Cancer Cells by Leaf Extract of Ashwagandha: Identification of aTumor Inhibitory Factor and The First Molecular Insights to its Effect’. Clinical Cancer Res ;13(7):2298-306
  • CC Deocaris, N Widodo, K Kaur, K Yamazaki, BG Shrestha,SC Kaul and R Wadhwa (2007). Mortalin sentisizes Human cancer cells to MKT-077 induced senescence. Cancer Lett , 18;252(2):259-269.
  • CC Deocaris, BG Shrestha, DC Kraft, K Yamazaki, SC Kaul, SIS Rattan, and R Wadhwa (2006). Geroprotection by Glycerol, Insights to its mechanism and Clinical potentials. Ann NY Acad Sci, 1067:488-492
  • BG Shrestha, T Iijima, Y Yamamoto, A Maekawa and T Tadokoro (2003). Evaluation of mustard seed and oil varieties as grown or used in Nepal. J for the Integrated Study of Dietary Habits, Vol. 14, No. 2